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In vitro substrate specificities of 3'-5' polymerases correlate with biological outcomes of tRNA 5'-editing reactions

Protozoan mitochondrial tRNAs (mt-tRNAs) are repaired by a process known as 5'-editing. Mt-tRNA sequencing revealed organism-specific patterns of editing G-U base pairs, wherein some species remove G-U base pairs during 5'-editing, while others retain G-U pairs in the edited tRNA. We teste...

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Udgivet i:FEBS Lett
Main Authors: Long, Yicheng, Jackman, Jane E.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524524/
https://ncbi.nlm.nih.gov/pubmed/26143376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2015.06.028
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