Niosomal carriers enhance oral bioavailability of carvedilol: effects of bile salt-enriched vesicles and carrier surface charge

Carvedilol (CRV) is an antihypertensive drug with both alpha and beta receptor blocking activity used to preclude angina and cardiac arrhythmias. To overcome the low, variable oral bioavailability of CRV, niosomal formulations were prepared and characterized: plain niosomes (without bile salts), bil...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Arzani, Gelareh, Haeri, Azadeh, Daeihamed, Marjan, Bakhtiari-Kaboutaraki, Hamid, Dadashzadeh, Simin
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524462/
https://ncbi.nlm.nih.gov/pubmed/26251598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S84703
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