A Simple and Sensitive HPLC Method for Fluorescence Quantitation of Doxorubicin in Micro-volume Plasma: Applications to Pharmacokinetic Studies in Rats

A validated HPLC method was developed to determine the doxorubicin concentration in a small volume of rat plasma (60 µL) with convenient fluorescence detection. Sample preparation includes a simple one-step liquid-liquid extraction using a minimum amount of organic solvent, with extraction recovery...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Iran J Pharm Res
Prif Awduron: Daeihamed, Marjan, Haeri, Azadeh, Dadashzadeh, Simin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Shaheed Beheshti University of Medical Sciences 2015
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499424/
https://ncbi.nlm.nih.gov/pubmed/26185503
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