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Inhibition of O-Linked N-Acetylglucosamine Transferase Reduces Replication of Herpes Simplex Virus and Human Cytomegalovirus

O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) is an essential cellular enzyme that posttranslationally modifies nuclear and cytoplasmic proteins via O-linked addition of a single N-acetylglucosamine (GlcNAc) moiety. Among the many targets of OGT is host cell factor 1 (HCF-1), a transcrip...

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Publicado en:J Virol
Main Authors: Angelova, Magdalena, Ortiz-Meoz, Rodrigo F., Walker, Suzanne, Knipe, David M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524265/
https://ncbi.nlm.nih.gov/pubmed/26041297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01002-15
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