Nonglycosylated G-Protein Vaccine Protects against Homologous and Heterologous Respiratory Syncytial Virus (RSV) Challenge, while Glycosylated G Enhances RSV Lung Pathology and Cytokine Levels

New efforts are under way to develop a vaccine against respiratory syncytial virus (RSV) that will provide protective immunity without the potential for vaccine-associated disease enhancement such as that observed in infants following vaccination with formalin-inactivated RSV vaccine. In addition to...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Fuentes, Sandra, Coyle, Elizabeth M., Golding, Hana, Khurana, Surender
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524247/
https://ncbi.nlm.nih.gov/pubmed/26018164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00133-15
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