Broadly Neutralizing Human Immunodeficiency Virus Type 1 Antibody Gene Transfer Protects Nonhuman Primates from Mucosal Simian-Human Immunodeficiency Virus Infection

Broadly neutralizing antibodies (bnAbs) can prevent lentiviral infection in nonhuman primates and may slow the spread of human immunodeficiency virus type 1 (HIV-1). Although protection by passive transfer of human bnAbs has been demonstrated in monkeys, durable expression is essential for its broad...

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Publicado en:J Virol
Main Authors: Saunders, Kevin O., Wang, Lingshu, Joyce, M. Gordon, Yang, Zhi-Yong, Balazs, Alejandro B., Cheng, Cheng, Ko, Sung-Youl, Kong, Wing-Pui, Rudicell, Rebecca S., Georgiev, Ivelin S., Duan, Lijie, Foulds, Kathryn E., Donaldson, Mitzi, Xu, Ling, Schmidt, Stephen D., Todd, John-Paul, Baltimore, David, Roederer, Mario, Haase, Ashley T., Kwong, Peter D., Rao, Srinivas S., Mascola, John R., Nabel, Gary J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2015
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524228/
https://ncbi.nlm.nih.gov/pubmed/26041300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00908-15
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