Phosphorylation of SAF-A/hnRNP-U Serine 59 by Polo-Like Kinase 1 Is Required for Mitosis

Scaffold attachment factor A (SAF-A), also called heterogenous nuclear ribonuclear protein U (hnRNP-U), is phosphorylated on serine 59 by the DNA-dependent protein kinase (DNA-PK) in response to DNA damage. Since SAF-A, DNA-PK catalytic subunit (DNA-PKcs), and protein phosphatase 6 (PP6), which inte...

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Publié dans:Mol Cell Biol
Auteurs principaux: Douglas, Pauline, Ye, Ruiqiong, Morrice, Nicholas, Britton, Sébastien, Trinkle-Mulcahy, Laura, Lees-Miller, Susan P.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2015
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524121/
https://ncbi.nlm.nih.gov/pubmed/25986610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01312-14
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