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Bimodal Interaction of Mammalian Polo-Like Kinase 1 and a Centrosomal Scaffold, Cep192, in the Regulation of Bipolar Spindle Formation

Serving as microtubule-organizing centers, centrosomes play a key role in forming bipolar spindles. The mechanism of how centrosomes promote bipolar spindle assembly in various organisms remains largely unknown. A recent study with Xenopus laevis egg extracts suggested that the Plk1 ortholog Plx1 in...

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Publicat a:Mol Cell Biol
Autors principals: Meng, Lingjun, Park, Jung-Eun, Kim, Tae-Sung, Lee, Eun Hye, Park, Suk-Youl, Zhou, Ming, Bang, Jeong K., Lee, Kyung S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524112/
https://ncbi.nlm.nih.gov/pubmed/26012549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00068-15
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