Impaired Epstein-Barr Virus-Specific Neutralizing Antibody Response during Acute Infectious Mononucleosis Is Coincident with Global B-Cell Dysfunction

Here we present evidence for previously unappreciated B-cell immune dysregulation during acute Epstein-Barr virus (EBV)-associated infectious mononucleosis (IM). Longitudinal analyses revealed that patients with acute IM have undetectable EBV-specific neutralizing antibodies and gp350-specific B-cel...

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Podrobná bibliografie
Vydáno v:J Virol
Hlavní autoři: Panikkar, Archana, Smith, Corey, Hislop, Andrew, Tellam, Nick, Dasari, Vijayendra, Hogquist, Kristin A., Wykes, Michelle, Moss, Denis J., Rickinson, Alan, Balfour, Henry H., Khanna, Rajiv
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524077/
https://ncbi.nlm.nih.gov/pubmed/26109734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01293-15
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