B cell-derived circulating granzyme B is a feature of acute infectious mononucleosis

Granzyme B (GzmB) is a serine protease best known for inducing target cell apoptosis when released by cytotoxic T lymphocytes (CTLs) or natural killer cells with pore-forming perforin. As a result, GzmB detected in the serum of virus-infected individuals has typically been attributed to these source...

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Detalhes bibliográficos
Publicado no:Clin Transl Immunology
Main Authors: Hagn, Magdalena, Panikkar, Archana, Smith, Corey, Balfour Jr, Henry H, Khanna, Rajiv, Voskoboinik, Ilia, Trapani, Joseph A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491623/
https://ncbi.nlm.nih.gov/pubmed/26191409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cti.2015.10
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