TPX2 phosphorylation maintains metaphase spindle length by regulating microtubule flux

A steady-state metaphase spindle maintains constant length, although the microtubules undergo intensive dynamics. Tubulin dimers are incorporated at plus ends of spindle microtubules while they are removed from the minus ends, resulting in poleward movement. Such microtubule flux is regulated by the...

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Dettagli Bibliografici
Pubblicato in:J Cell Biol
Autori principali: Fu, Jingyan, Bian, Minglei, Xin, Guangwei, Deng, Zhaoxuan, Luo, Jia, Guo, Xiao, Chen, Hao, Wang, Yao, Jiang, Qing, Zhang, Chuanmao
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2015
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523612/
https://ncbi.nlm.nih.gov/pubmed/26240182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201412109
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