TPX2 phosphorylation maintains metaphase spindle length by regulating microtubule flux

A steady-state metaphase spindle maintains constant length, although the microtubules undergo intensive dynamics. Tubulin dimers are incorporated at plus ends of spindle microtubules while they are removed from the minus ends, resulting in poleward movement. Such microtubule flux is regulated by the...

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Detalles Bibliográficos
Publicado en:J Cell Biol
Main Authors: Fu, Jingyan, Bian, Minglei, Xin, Guangwei, Deng, Zhaoxuan, Luo, Jia, Guo, Xiao, Chen, Hao, Wang, Yao, Jiang, Qing, Zhang, Chuanmao
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2015
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523612/
https://ncbi.nlm.nih.gov/pubmed/26240182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201412109
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