TPX2 phosphorylation maintains metaphase spindle length by regulating microtubule flux

A steady-state metaphase spindle maintains constant length, although the microtubules undergo intensive dynamics. Tubulin dimers are incorporated at plus ends of spindle microtubules while they are removed from the minus ends, resulting in poleward movement. Such microtubule flux is regulated by the...

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Bibliografiske detaljer
Udgivet i:J Cell Biol
Main Authors: Fu, Jingyan, Bian, Minglei, Xin, Guangwei, Deng, Zhaoxuan, Luo, Jia, Guo, Xiao, Chen, Hao, Wang, Yao, Jiang, Qing, Zhang, Chuanmao
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2015
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523612/
https://ncbi.nlm.nih.gov/pubmed/26240182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201412109
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