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Ceramide metabolism regulates autophagy and apoptotic-cell death induced by melatonin in liver cancer cells

Autophagy is a process that maintains homeostasis during stress, although it also contributes to cell death under specific contexts. Ceramides have emerged as important effectors in the regulation of autophagy, mediating the crosstalk with apoptosis. Melatonin induces apoptosis of cancer cells; howe...

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Détails bibliographiques
Publié dans:J Pineal Res
Auteurs principaux: Ordoñez, Raquel, Fernández, Ana, Prieto-Domínguez, Néstor, Martínez, Laura, García-Ruiz, Carmen, Fernández-Checa, José C., Mauriz, José L., González-Gallego, Javier
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523438/
https://ncbi.nlm.nih.gov/pubmed/25975536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jpi.12249
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