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Dynasore enhances the formation of mitochondrial antiviral signalling aggregates and endocytosis-independent NF-ĸB activation
BACKGROUND AND PURPOSE: Dynasore has been used extensively as an inhibitor of clathrin-mediated endocytosis. While studying the role of endocytosis in LPS-induced signalling events, we discovered that dynasore itself induced activation of NF-κB, independently of its effects on endocytosis and withou...
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| Publicat a: | Br J Pharmacol |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley & Sons, Ltd
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4523333/ https://ncbi.nlm.nih.gov/pubmed/25850711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13162 |
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