The kinase IKKβ regulates a STING and NF-ĸB-dependent antiviral response pathway in Drosophila

Antiviral immunity in Drosophila involves RNA interference and poorly characterized inducible responses. Here, we showed that two components of the IMD pathway, the kinase dIKKβ and the transcription factor Relish, were required to control infection by two picorna-like viruses. We identified a set o...

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Publicado no:Immunity
Main Authors: Goto, Akira, Okado, Kiyoshi, Martins, Nelson, Cai, Hua, Barbier, Vincent, Lamiable, Olivier, Troxler, Laurent, Santiago, Estelle, Kuhn, Lauriane, Paik, Donggi, Silverman, Neal, Holleufer, Andreas, Hartmann, Rune, Liu, Jiyong, Peng, Tao, Hoffmann, Jules A., Meignin, Carine, Daeffler, Laurent, Imler, Jean-Luc
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6267954/
https://ncbi.nlm.nih.gov/pubmed/30119996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.07.013
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