The kinase IKKβ regulates a STING and NF-ĸB-dependent antiviral response pathway in Drosophila

Antiviral immunity in Drosophila involves RNA interference and poorly characterized inducible responses. Here, we showed that two components of the IMD pathway, the kinase dIKKβ and the transcription factor Relish, were required to control infection by two picorna-like viruses. We identified a set o...

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Publicat a:Immunity
Autors principals: Goto, Akira, Okado, Kiyoshi, Martins, Nelson, Cai, Hua, Barbier, Vincent, Lamiable, Olivier, Troxler, Laurent, Santiago, Estelle, Kuhn, Lauriane, Paik, Donggi, Silverman, Neal, Holleufer, Andreas, Hartmann, Rune, Liu, Jiyong, Peng, Tao, Hoffmann, Jules A., Meignin, Carine, Daeffler, Laurent, Imler, Jean-Luc
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6267954/
https://ncbi.nlm.nih.gov/pubmed/30119996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.07.013
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