Activation of PPAR-δ induces microRNA-100 and decreases the uptake of very low-density lipoprotein in endothelial cells

BACKGROUND AND PURPOSE: Increased level of very low-density lipoprotein (VLDL) is a key feature of the metabolic syndrome and is associated with cardiovascular diseases. PPAR-δ agonists play a protective role in lipid metabolism and vascular function. In this study, we aimed to investigate the role...

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Veröffentlicht in:Br J Pharmacol
Hauptverfasser: Fang, Xi, Fang, Li, Liu, Ao, Wang, Xiaohong, Zhao, Beilei, Wang, Nanping
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Ltd 2015
Schlagworte:
Research Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523331/
https://ncbi.nlm.nih.gov/pubmed/25857370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13160
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