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PPARδ is a very low-density lipoprotein sensor in macrophages

Although triglyceride-rich particles, such as very low-density lipoprotein (VLDL), contribute significantly to human atherogenesis, the molecular basis for lipoprotein-driven pathogenicity is poorly understood. We demonstrate that in macrophages, VLDL functions as a transcriptional regulator via the...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Chawla, Ajay, Lee, Chih-Hao, Barak, Yaacov, He, Weimin, Rosenfeld, John, Liao, Debbie, Han, Jungyeob, Kang, Heonjoong, Evans, Ronald M.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298762/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12540828/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0337331100
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