The YopB protein of Yersinia pseudotuberculosis is essential for the translocation of Yop effector proteins across the target cell plasma membrane and displays a contact-dependent membrane disrupting activity.

During infection of cultured epithelial cells, surface-located Yersinia pseudotuberculosis deliver Yop (Yersinia outer protein) virulence factors into the cytoplasm of the target cell. A non-polar yopB mutant strain displays a wild-type phenotype with respect to in vitro Yop regulation and secretion...

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Bibliografske podrobnosti
Main Authors: Håkansson, S, Schesser, K, Persson, C, Galyov, E E, Rosqvist, R, Homblé, F, Wolf-Watz, H
Format: Artigo
Jezik:Inglês
Izdano: 1996
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC452329/
https://ncbi.nlm.nih.gov/pubmed/8918459
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