The YopB protein of Yersinia pseudotuberculosis is essential for the translocation of Yop effector proteins across the target cell plasma membrane and displays a contact-dependent membrane disrupting activity.

During infection of cultured epithelial cells, surface-located Yersinia pseudotuberculosis deliver Yop (Yersinia outer protein) virulence factors into the cytoplasm of the target cell. A non-polar yopB mutant strain displays a wild-type phenotype with respect to in vitro Yop regulation and secretion...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Håkansson, S, Schesser, K, Persson, C, Galyov, E E, Rosqvist, R, Homblé, F, Wolf-Watz, H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452329/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8918459/
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