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Wdr1-mediated cell shape dynamics and cortical tension are essential for epidermal planar cell polarity

During mouse development, core planar cell polarity (PCP) proteins become polarized in the epidermal plane to guide angling/morphogenesis of hair follicles. How PCP is established is poorly understood. Here, we identify a key role for Wdr1 (also known as Aip1), an F-actin-binding protein that enhanc...

詳細記述

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書誌詳細
出版年:Nat Cell Biol
主要な著者: Luxenburg, Chen, Heller, Evan, Pasolli, H. Amalia, Chai, Sophia, Nikolova, Maria, Stokes, Nicole, Fuchs, Elaine
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523270/
https://ncbi.nlm.nih.gov/pubmed/25915128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3146
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