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Mutation-induced protein interaction kinetics changes affect apoptotic network dynamic properties and facilitate oncogenesis
It has been a consensus in cancer research that cancer is a disease caused primarily by genomic alterations, especially somatic mutations. However, the mechanism of mutation-induced oncogenesis is not fully understood. Here, we used the mitochondrial apoptotic pathway as a case study and performed a...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4522770/ https://ncbi.nlm.nih.gov/pubmed/26170328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502126112 |
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