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Linear diffusion of the restriction endonuclease EcoRV on DNA is essential for the in vivo function of the enzyme.

Linear diffusion along DNA is a mechanism of enhancing the association rates of proteins to their specific recognition sites on DNA. It has been demonstrated for several proteins in vitro, but to date in no case in vivo. Here we show that the restriction endonuclease EcoRV slides along the DNA, scan...

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Udgivet i:EMBO J
Principais autores: Jeltsch, A, Wenz, C, Stahl, F, Pingoud, A
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452250/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8890184/
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