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Complementary change in cis determinants and trans factors in the evolution of an mRNP stability complex.

RNA-protein (RNP) complexes play significant roles in the fate and expression of mRNAs. The prolonged half-life of human alpha-globin mRNA, a major determinant of normal erythroid differentiation, is dependent on the assembly of a sequence-specific 3'-untranslated region (3'UTR) RNP (alpha...

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Publicat a:EMBO J
Autors principals: Wang, X, Liebhaber, S A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452243/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8890177/
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