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BENEFICIAL EFFECTS OF MINERALOCORTICOID RECEPTOR BLOCKADE IN EXPERIMENTAL NON-ALCOHOLIC STEATOHEPATITIS

BACKGROUND: Therapeutic options to treat Non-alcoholic steatohepatitis (NASH) are limited. Mineralocorticoid receptor (MR) activation could play a role in hepatic fibrogenesis and its modulation could be beneficial for NASH. AIM: To investigate whether eplerenone, a specific MR antagonist, ameliorat...

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Detalhes bibliográficos
Publicado no:Liver Int
Main Authors: Pizarro, Margarita, Solís, Nancy, Quintero, Pablo, Barrera, Francisco, Cabrera, Daniel, Santiago, Pamela Rojasde, Arab, Juan Pablo, Padilla, Oslando, Roa, Juan Carlos, Moshage, Han, Wree, Alexander, Inzaugarat, Eugenia, Feldstein, Ariel E., Fardella, Carlos E., Baudrand, Rene, Riquelme, Arnoldo, Arrese, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522413/
https://ncbi.nlm.nih.gov/pubmed/25646700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.12794
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