Design and Evaluation of Tumor-Specific Dendrimer Epigenetic Therapeutics

Histone deacetylase inhibitors (HDACi) are promising therapeutics for cancer. HDACi alter the epigenetic state of tumors and provide a unique approach to treat cancer. Although studies with HDACi have shown promise in some cancers, variable efficacy and off-target effects have limited their use. To...

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Vydáno v:ChemistryOpen
Hlavní autoři: Zong, Hong, Shah, Dhavan, Selwa, Katherine, Tsuchida, Ryan E, Rattan, Rahul, Mohan, Jay, Stein, Adam B, Otis, James B, Goonewardena, Sascha N
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Ltd 2015
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Full Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522184/
https://ncbi.nlm.nih.gov/pubmed/26246996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201402141
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