TODRA, a lncRNA at the RAD51 Locus, Is Oppositely Regulated to RAD51, and Enhances RAD51-Dependent DSB (Double Strand Break) Repair

Expression of RAD51, a crucial player in homologous recombination (HR) and DNA double-strand break (DSB) repair, is dysregulated in human tumors, and can contribute to genomic instability and tumor progression. To further understand RAD51 regulation we functionally characterized a long non-coding (l...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Gazy, Inbal, Zeevi, David A., Renbaum, Paul, Zeligson, Sharon, Eini, Lital, Bashari, Dana, Smith, Yoav, Lahad, Amnon, Goldberg, Michal, Ginsberg, Doron, Levy-Lahad, Ephrat
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521930/
https://ncbi.nlm.nih.gov/pubmed/26230935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134120
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