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Ganetespib: research and clinical development
Under stressful conditions, the heat shock protein 90 (HSP90) molecular chaperone protects cellular proteins (client proteins) from degradation via the ubiquitin-proteasome pathway. HSP90 expression is upregulated in cancers, and this contributes to the malignant phenotype of increased proliferation...
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| Pubblicato in: | Onco Targets Ther |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Dove Medical Press
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4521669/ https://ncbi.nlm.nih.gov/pubmed/26244021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S65804 |
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