AAA proteases with catalytic sites on opposite membrane surfaces comprise a proteolytic system for the ATP-dependent degradation of inner membrane proteins in mitochondria.

The mechanism of selective protein degradation of membrane proteins in mitochondria has been studied employing a model protein that is subject to rapid proteolysis within the inner membrane. Protein degradation was mediated by two different proteases: (i) the m-AAA protease, a protease complex consi...

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Bibliographic Details
Main Authors: Leonhard, K, Herrmann, J M, Stuart, R A, Mannhaupt, G, Neupert, W, Langer, T
Format: Artigo
Language:Inglês
Published: 1996
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC452147/
https://ncbi.nlm.nih.gov/pubmed/8861950
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