Identification of a titratable lysine residue that determines sensitivity of kidney potassium channels (ROMK) to intracellular pH.

Potassium (K+) homeostasis is controlled by the secretion of K+ ions across the apical membrane of renal collecting duct cells through a low-conductance inwardly rectifying K+ channel. The sensitivity of this channel to intracellular pH is particularly high and assumed to play a key role in K+ homeo...

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Main Authors: Fakler, B, Schultz, J H, Yang, J, Schulte, U, Brandle, U, Zenner, H P, Jan, L Y, Ruppersberg, J P
Format: Artigo
Jezik:Inglês
Izdano: 1996
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC452131/
https://ncbi.nlm.nih.gov/pubmed/8861938
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