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Mutation spectrum and genotype–phenotype correlation of hearing loss patients caused by SLC26A4 mutations in the Japanese: a large cohort study

Mutations in SLC26A4 cause a broad phenotypic spectrum, from typical Pendred syndrome to nonsyndromic hearing loss associated with enlarged vestibular aqueduct. Identification of these mutations is important for accurate diagnosis, proper medical management and appropriate genetic counseling and req...

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Detalhes bibliográficos
Publicado no:J Hum Genet
Main Authors: Miyagawa, Maiko, Nishio, Shin-ya, Usami, Shin-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521295/
https://ncbi.nlm.nih.gov/pubmed/24599119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jhg.2014.12
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