In Vivo Reprogramming of Striatal NG2 Glia into Functional Neurons that Integrate into Local Host Circuitry

The possibility of directly converting non-neuronal cells into neurons in situ in the brain would open therapeutic avenues aimed at repairing the brain after injury or degenerative disease. We have developed an adeno-associated virus (AAV)-based reporter system that allows selective GFP labeling of...

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Vydáno v:Cell Rep
Hlavní autoři: Torper, Olof, Ottosson, Daniella Rylander, Pereira, Maria, Lau, Shong, Cardoso, Tiago, Grealish, Shane, Parmar, Malin
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521079/
https://ncbi.nlm.nih.gov/pubmed/26166567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.06.040
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