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Lipopolysaccharides Promote S-Nitrosylation and Proteasomal Degradation of Liver Kinase B1 (LKB1) in Macrophages in Vivo

LKB1 (liver kinase B1) plays important roles in tumor suppression, energy metabolism, and, recently, in innate immune responses. However, how LKB1 is regulated under physiological or pathological conditions is still unclear. Here, we report that LKB1 protein (but not mRNA) was decreased in both LPS-...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Biol Chem
Main Authors: Liu, Zhaoyu, Dai, Xiaoyan, Zhu, Huaiping, Zhang, Miao, Zou, Ming-Hui
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521026/
https://ncbi.nlm.nih.gov/pubmed/26070564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.649210
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