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Regulation of Iron Metabolism by Hepcidin under Conditions of Inflammation

Iron is a redox-active metal required as a cofactor in multiple metalloproteins essential for a host of life processes. The metal is highly toxic when present in excess and must be strictly regulated to prevent tissue and organ damage. Hepcidin, a molecule first characterized as an antimicrobial pep...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
1. Verfasser: Schmidt, Paul J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521019/
https://ncbi.nlm.nih.gov/pubmed/26055723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R115.650150
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