Loss of Microtubule-Associated Protein 2 Immunoreactivity Linked to Dendritic Spine Loss in Schizophrenia

BACKGROUND: Microtubule-associated protein 2 (MAP2) is a neuronal protein that plays a role in maintaining dendritic structure through its interaction with microtubules. In schizophrenia (Sz), a number of studies have revealed that MAP2’s typically robust immunoreactivity (IR) is significantly reduc...

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Veröffentlicht in:Biol Psychiatry
Hauptverfasser: Shelton, Micah A., Newman, Jason T., Gu, Hong, Sampson, Allan R., Fish, Kenneth N., MacDonald, Matthew L, Moyer, Caitlin E., DiBitetto, James V, Dorph-Petersen, Karl-Anton, Penzes, Peter, Lewis, David A., Sweet, Robert A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520801/
https://ncbi.nlm.nih.gov/pubmed/25818630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2014.12.029
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