Altered Glutamate Protein Co-Expression Network Topology Linked to Spine Loss in the Auditory Cortex of Schizophrenia

BACKGROUND: Impaired glutamatergic signaling is believed to underlie auditory cortex pyramidal neuron dendritic spine loss and auditory symptoms in schizophrenia. Many schizophrenia risk loci converge on the synaptic glutamate signaling network. We therefore hypothesized that alterations in glutamat...

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I publikationen:Biol Psychiatry
Huvudupphovsmän: MacDonald, Matthew L., Ding, Ying, Newman, Jason, Hemby, Scott, Penzes, Peter, Lewis, David A., Yates, Nathan, Sweet, Robert A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428927/
https://ncbi.nlm.nih.gov/pubmed/25433904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2014.09.006
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