Ubiquilin 1 Promotes IFN-γ-Induced Xenophagy of Mycobacterium tuberculosis

The success of Mycobacterium tuberculosis (Mtb) as a pathogen rests upon its ability to grow intracellularly in macrophages. Interferon-gamma (IFN-γ) is critical in host defense against Mtb and stimulates macrophage clearance of Mtb through an autophagy pathway. Here we show that the host protein ub...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Sakowski, Erik T., Koster, Stefan, Portal Celhay, Cynthia, Park, Heidi S., Shrestha, Elina, Hetzenecker, Stefanie E., Maurer, Katie, Cadwell, Ken, Philips, Jennifer A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520715/
https://ncbi.nlm.nih.gov/pubmed/26225865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005076
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