Construction, expression, and immunogenicity of the Schistosoma mansoni P28 glutathione S-transferase as a genetic fusion to tetanus toxin fragment C in a live Aro attenuated vaccine strain of Salmonella.

A vector has been constructed to allow genetic fusions of guest antigens via a hinge domain to the C terminus of the highly immunogenic C fragment of tetanus toxin. A fusion has been constructed with the gene encoding the protective 28-kDa glutathione S-transferase (EC 2.5.1.18) from Schistosoma man...

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Autores principales: Khan, C M, Villarreal-Ramos, B, Pierce, R J, Riveau, G, Demarco de Hormaeche, R, McNeill, H, Ali, T, Fairweather, N, Chatfield, S, Capron, A
Formato: Artigo
Lenguaje:Inglês
Publicado: 1994
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC45207/
https://ncbi.nlm.nih.gov/pubmed/7972044
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