Construction, expression, and immunogenicity of the Schistosoma mansoni P28 glutathione S-transferase as a genetic fusion to tetanus toxin fragment C in a live Aro attenuated vaccine strain of Salmonella.

A vector has been constructed to allow genetic fusions of guest antigens via a hinge domain to the C terminus of the highly immunogenic C fragment of tetanus toxin. A fusion has been constructed with the gene encoding the protective 28-kDa glutathione S-transferase (EC 2.5.1.18) from Schistosoma man...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Khan, C M, Villarreal-Ramos, B, Pierce, R J, Riveau, G, Demarco de Hormaeche, R, McNeill, H, Ali, T, Fairweather, N, Chatfield, S, Capron, A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45207/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7972044/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.23.11261
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