Synergistic antiproliferative effect of imatinib and adriamycin in platelet-derived growth factor receptor-expressing osteosarcoma cells

Osteosarcoma (OS) is the most frequent primary solid malignant tumor of bone. Its prognosis remains poor in the substantial proportion of patients who do not respond to chemotherapy and novel therapeutic options are therefore needed. We previously established a mouse model that mimics the aggressive...

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Pubblicato in:Cancer Sci
Autori principali: Yamaguchi, Sayaka I, Ueki, Arisa, Sugihara, Eiji, Onishi, Nobuyuki, Yaguchi, Tomonori, Kawakami, Yutaka, Horiuchi, Keisuke, Morioka, Hideo, Matsumoto, Morio, Nakamura, Masaya, Muto, Akihiro, Toyama, Yoshiaki, Saya, Hideyuki, Shimizu, Takatsune
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Ltd 2015
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520639/
https://ncbi.nlm.nih.gov/pubmed/25940371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12686
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