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Functional interplay between MYCN, NCYM, and OCT4 promotes aggressiveness of human neuroblastomas

Neuroblastoma is a pediatric solid tumor that originates from embryonic neural crest cells. The MYCN gene locus is frequently amplified in unfavorable neuroblastomas, and the gene product promotes the progression of neuroblastomas. However, the molecular mechanisms by which MYCN amplification contri...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Kaneko, Yoshiki, Suenaga, Yusuke, Islam, S M Rafiqul, Matsumoto, Daisuke, Nakamura, Yohko, Ohira, Miki, Yokoi, Sana, Nakagawara, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520635/
https://ncbi.nlm.nih.gov/pubmed/25880909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12677
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