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The beta-globin locus control region enhances transcription of but does not confer position-independent expression onto the lacZ gene in transgenic mice.

The beta-globin locus control region (LCR) confers high levels of position-independent, copy number-dependent expression onto globin transgenes. Here > 40 independent transgenic mouse lines and founders that carried the LCR in cis with the beta-globin gene promoter driving a lacZ reporter gene we...

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Detalhes bibliográficos
Main Authors: Guy, L G, Kothary, R, DeRepentigny, Y, Delvoye, N, Ellis, J, Wall, L
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC452030/
https://ncbi.nlm.nih.gov/pubmed/8670875
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