SREBP-1 Mediates Angiotensin II-Induced TGF-β1 Upregulation and Glomerular Fibrosis

Angiotensin II is an important mediator of CKD of diverse etiology. A common pathologic feature of CKD is glomerular fibrosis, a central mediator of which is the profibrotic cytokine TGF-β. The mechanisms underlying the induction of TGF-β and matrix by angiotensin II are not completely understood. R...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Wang, Tony N., Chen, Xing, Li, Renzhong, Gao, Bo, Mohammed-Ali, Zahraa, Lu, Chao, Yum, Victoria, Dickhout, Jeffrey G., Krepinsky, Joan C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2015
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520156/
https://ncbi.nlm.nih.gov/pubmed/25398788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013121332
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados