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A functional variant in the UBE2B gene promoter is associated with idiopathic azoospermia
BACKGROUND: A variety of genetic variants lead to abnormal human spermatogenesis. The ubiquitin-conjugating enzyme E2B (UBE2B) plays a significant role in spermatogenesis as Ube2b-knockout male mice are infertile. METHODS: In this study, we sequenced the exon and promoter region of UBE2B in 776 pati...
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| Vydáno v: | Reprod Biol Endocrinol |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4520152/ https://ncbi.nlm.nih.gov/pubmed/26223869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12958-015-0074-4 |
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