TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors.

Nuclear receptors (NRs) act as ligand-inducible transcription factors which regulate the expression of target genes upon binding to cognate response elements. The ligand-dependent activity of the NR activation function AF-2 is believed to be mediated to the transcription machinery through transcript...

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Bibliographic Details
Main Authors: Voegel, J J, Heine, M J, Zechel, C, Chambon, P, Gronemeyer, H
Format: Artigo
Language:Inglês
Published: 1996
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC452006/
https://ncbi.nlm.nih.gov/pubmed/8670870
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