Repression of arterial genes in hemogenic endothelium is sufficient for haematopoietic fate acquisition

Changes in cell fate and identity are essential for endothelial-to-haematopoietic transition (EHT), an embryonic process that generates the first adult populations of haematopoietic stem cells (HSCs) from hemogenic endothelial cells. Dissecting EHT regulation is a critical step towards the productio...

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Vydáno v:Nat Commun
Hlavní autoři: Lizama, Carlos O., Hawkins, John S., Schmitt, Christopher E., Bos, Frank L., Zape, Joan P., Cautivo, Kelly M., Borges Pinto, Hugo, Rhyner, Alexander M., Yu, Hui, Donohoe, Mary E., Wythe, Joshua D., Zovein, Ann C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Pub. Group 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519987/
https://ncbi.nlm.nih.gov/pubmed/26204127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8739
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