Scl represses cardiomyogenesis in prospective hemogenic endothelium and endocardium

Endothelium in embryonic hematopoietic tissues generates hematopoietic stem/progenitor cells; however, it is unknown how its unique potential is specified. We show that transcription factor Scl/Tal1 is essential for both establishing the hematopoietic transcriptional program in hemogenic endothelium...

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Main Authors: Van Handel, Ben, Montel-Hagen, Amélie, Sasidharan, Rajkumar, Nakano, Haruko, Ferrari, Roberto, Boogerd, Cornelis J., Schredelseker, Johann, Wang, Yanling, Hunter, Sean, Org, Tõnis, Zhou, Jian, Li, Xinmin, Pellegrini, Matteo, Chen, Jau-Nian, Orkin, Stuart H., Kurdistani, Siavash K., Evans, Sylvia M., Nakano, Atsushi, Mikkola, Hanna K. A.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624753/
https://ncbi.nlm.nih.gov/pubmed/22863011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.06.026
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