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Increased catalase expression improves muscle function in mdx mice

It has been well established that oxidative stress contributes to pathology associated with Duchenne muscular dystrophy (DMD). I hypothesized that overexpression of the antioxidant enzyme catalase would improve muscle function in the mdx mouse, the mouse model of DMD. To test this hypothesis, neonat...

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Bibliographic Details
Published in:Exp Physiol
Main Author: Selsby, Joshua T.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519830/
https://ncbi.nlm.nih.gov/pubmed/21041317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/expphysiol.2010.054379
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