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Genome-wide construction of a series of designed segmental aneuploids in Saccharomyces cerevisiae

Segmental aneuploidy can play an important role in environmental adaptation. However, study of segmental aneuploids is severely hampered by the difficulty of creating them in a designed fashion. Here, we describe a PCR-mediated chromosome duplication (PCDup) technology that enables the generation of...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Natesuntorn, Waranya, Iwami, Kotaro, Matsubara, Yuki, Sasano, Yu, Sugiyama, Minetaka, Kaneko, Yoshinobu, Harashima, Satoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519793/
https://ncbi.nlm.nih.gov/pubmed/26224198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12510
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