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Genome-wide construction of a series of designed segmental aneuploids in Saccharomyces cerevisiae

Segmental aneuploidy can play an important role in environmental adaptation. However, study of segmental aneuploids is severely hampered by the difficulty of creating them in a designed fashion. Here, we describe a PCR-mediated chromosome duplication (PCDup) technology that enables the generation of...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Natesuntorn, Waranya, Iwami, Kotaro, Matsubara, Yuki, Sasano, Yu, Sugiyama, Minetaka, Kaneko, Yoshinobu, Harashima, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519793/
https://ncbi.nlm.nih.gov/pubmed/26224198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12510
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