Genome-wide mapping of DNA hydroxymethylation in osteoarthritic chondrocytes

OBJECTIVE: To examine genome-wide 5hmC distribution in osteoarthritic (OA) and normal chondrocytes to investigate the effect on OA-specific gene expression. METHODS: Cartilage was obtained from OA patients undergoing total knee arthroplasty or control patients undergoing anterior cruciate ligament r...

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Udgivet i:Arthritis Rheumatol
Main Authors: Taylor, Sarah E. B., Li, Ye Henry, Wong, Wing H., Bhutani, Nidhi
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519426/
https://ncbi.nlm.nih.gov/pubmed/25940674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39179
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